The connection between iodine and Hashimoto’s disease has been one of the most requested topics that I cover, so I’d like to present the research on this topic, so we can set the record straight. Please be aware that none of this is my opinion but rather a detailed analysis of what the scientific literature currently presents.
Your body has about 15 to 20 mg of iodine and 70 to 80% of it resides in the thyroid gland. Iodine is transported into the thyroid gland through the sodium-iodine symporter or NIS. The thyroid peroxidase enzyme oxidizes iodine which is then integrated into thyroglobulin resulting in the production of thyroxine (T4) and triiodothyronine (T3). Thyroid stimulating hormone (TSH) regulates this process.
Your thyroid only needs 150 to 250 micrograms a day of iodine to function properly. Once iodine intake exceeds this range, hypothyroidism and autoimmune thyroid disease may occur in some individuals.
Inflammation is at the core of most chronic illnesses including hypothyroidism and Hashimoto’s disease. But how exactly does inflammation cause hypothyroidism? Nonthyroidal illness syndrome (NTIS) is the state in which inflammation causes negative changes to thyroid hormone including low T3 and increased reverse T3 (rT3). T3 is the most active form of thyroid hormone and rT3 actually blocks T3 receptors so inflammation can really knock out thyroid function. TSH levels however stay relatively “normal” in NTIS thus leaving many patients with the symptoms of hypothyroidism but no diagnosis since no one is checking their T3 or rT3 levels.
The authors begin by stating that subclinical hypothyroidism is characterized by “normal” T4, T3, Free T4, and Free T3 with an elevated TSH. And these patients have an increased risk of cholesterol abnormalities, heart disease, mental illness, and pregnancy complications even though their symptoms are relatively mild.
Is there a connection among Hashimoto’s disease, hypothyroidism, and small intestinal bacterial overgrowth also known as SIBO? Does Hashimoto’s disease cause SIBO or does SIBO cause Hashimoto’s? I’ll answer these questions in my latest research review below.
There isn’t a lot of research, only two papers actually, on the specific connection between Hashimoto’s disease and SIBO which I’ll cover in this article. There are more papers on the connection between hypothyroidism and SIBO without mention of Hashimoto’s and the basic conclusion of those papers is that hypothyroidism is connected to SIBO because gastric motility is decreased in hypothyroidism. Decreased gastric motility basically means the food you eat is moving through the bowels to slowly so bacteria can build-up in the small intestine.
Are you doing everything right for your Hashimoto’s disease and hypothyroidism but still experiencing fatigue? A chain is only as strong as it’s weakest link and the b-vitamin thiamine is an important link in thyroid function and energy production that could improve Hashimoto’s disease-related fatigue. Restrictive diets like the Autoimmune Paleo Diet, gluten-free diet, and ketogenic diet can possibly lead to a thiamine deficiency if there isn’t enough variety in the diet. Once this important vitamin becomes deficient, a number symptoms can appear as well as sluggish thyroid function.
In this episode of The Dr. Hedberg Show, I interviewed Andrea Nakayama in a discussion about strategies for healing Hashimoto’s disease. We talked about her “3 Tiers to Epigenetic Mastery” and how they relate to Hashimoto’s disease and thyroid health. Within the 3 tiers we discussed stress, gut health, infections, micronutrient deficiencies, adverse childhood experiences, SIBO, reproductive hormones, goitrogens, iodine, and all the various diets that people are following these days.
Andrea is a clinician but also a Hashimoto’s patient so it was a real pleasure to get her insight and expertise on healing Hashimoto’s disease.
In this episode of The Dr. Hedberg Show, I interview Dr. Izabella Wentz about her new book, “Hashimoto’s Food Pharmacology.” We had a great talk about Hashimoto’s disease, Dr. Wentz’s Hashimoto’s healing journey, foods that can help heal Hashimoto’s disease, green smoothies, bone broth, and some recipes that can help heal Hashimoto’s disease.
I highly recommend all of Dr. Wentz’s books and her new book will help you make food easier and healthier so you can heal your Hashimoto’s disease. Read more