In this episode of Functional Medicine Research I interview Dr. Kara Fitzgerald about her book, “The Methylation Diet” and a preview of her upcoming study on The Methylation Diet. We had a great discussion about topics like methylation and diet, MTHFR, COMT, SAMe, methylated folate and B12, homocysteine, epigenetics and much more.
The MTHFR test or methylenetetrahydrofolate reductase test has become extremely popular due to a number of alternative medicine practitioners promoting it as the source of many chronic illnesses. But is it something you should worry about?
This test is basically looking for two types of genetic mutations known as C677T and A1298C that affect the MTHFR enzyme involved in folate metabolism in your body.
Proper MTHFR enzyme function ensures that homocysteine is properly metabolized to the amino acid methionine which then makes SAMe. SAMe is known as the “universal methyl donor” which is extremely important for serotonin, melatonin and your DNA.
Folate is a B-vitamin and is important because it is at the heart of metabolism and the production of all your cells. Without it, nothing really works well so our list of symptoms and health problems would be extensive.