Inflammation is at the core of most chronic illnesses including hypothyroidism and Hashimoto’s disease. But how exactly does inflammation cause hypothyroidism? Nonthyroidal illness syndrome (NTIS) is the state in which inflammation causes negative changes to thyroid hormone including low T3 and increased reverse T3 (rT3). T3 is the most active form of thyroid hormone and rT3 actually blocks T3 receptors so inflammation can really knock out thyroid function. TSH levels however stay relatively “normal” in NTIS thus leaving many patients with the symptoms of hypothyroidism but no diagnosis since no one is checking their T3 or rT3 levels.
In this post I’ll cover everything you need to know about ferritin and hypothyroidism. The ferritin test is a simple blood test and it is one of the most important tests you should have if you have Hashimoto’s disease, Graves’ disease, and hypothyroidism. Ferritin is a storage form of iron and the ferritin level test can tell you if your iron stores are low and need to be increased. The ferritin test is rarely ordered by conventional doctors so many patients are left with the signs and symptoms of hypothyroidism when it is actually their low ferritin levels that are causing their health problems. The first issue with iron is that iron deficiency may be quite severe but blood markers such as hemoglobin and the red blood cell count may be normal. This leaves many patients, especially women, misdiagnosed as not having anemia.
The thyroid is a small gland that lies in the neck about the level of the Adam’s apple and weighs approximately one ounce. It produces thyroid hormone and calcitonin. The parathyroid glands are very small and lie on the outside portion of the thyroid gland and secrete parathyroid hormone. Thyroid hormone ignites your metabolism so you can burn fat and produce energy. We will be focusing on thyroid hormone.
The thyroid gland is stimulated to make thyroid hormone by thyroid-stimulating hormone (TSH) which is produced in the pituitary gland located in the brain. The pituitary is controlled by the hypothalamus in the brain which monitors the amount of circulating thyroid hormone. Iodine must enter the thyroid gland through a transport system that is repaired with the intake of vitamin C. There is usually about 20-30 mg of iodine in the body and 75 percent of it is stored in the thyroid. In addition to iodine, iron, tyrosine, selenium, vitamin E, vitamin C, vitamin D, magnesium, zinc, copper, and vitamins B2, B3, and B6 are required for thyroid hormone production. Read more